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An albino ferret getting caught off guard while yawningFerrets spend 14 to 18 hours a day sleeping, but when awake they are very active, exploring their surroundings relentlessly. Ferrets are naturally crepuscular, meaning they are most active during dawn and dusk. If kept in a cage, they should be let out for a few hours daily to get exercise and satisfy their curiosity. When ferrets are kept in their cages for too long, their walking ability can be affected, and they may become subject to depression or "cage stress." Ferrets, like cats, can use a litter box with training, though are not always completely litter box trainable.

Ferrets are also fine backyard companions and especially enjoy "helping" their owners in the garden. However, they should not be allowed to wander; ferrets are fearless to the point of foolishness and will get into whatever holes they will find, including storm drains. Whenever they are outside, they should be closely supervised and preferably kept on a harness leash designed for ferrets. There are different types of harnesses, and some ferrets prefer certain kinds. The H-shaped harness is the most popular. Collars will not work for ferrets as they do for dogs; a ferret can easily slip out of a collar because their heads are about the same width as their necks.

Additional care should be taken during mosquito and tick season, as ferrets are susceptible to the diseases carried by these parasites. Ticks can attach themselves and begin to draw blood. When the tick gets full, it regurgitates some blood and tick saliva back into the ferret, which is how Lyme and other diseases can be transmitted. Ordinarily, the regurgitation happens between five to 24 hours after the tick attaches. The key to keeping a ferret healthy is early removal of ticks using proper methods to avoid tick regurgitation, and prevention when in environments where encountering ticks is likely. Mosquitoes for their part can carry heart worms and the West Nile virus. Fleas can cause extreme skin irritation and can be intermediate hosts for tapeworms, one of which could potentially kill a ferret because of the ferret's small size. Also because of their small size, ferrets can also be regarded as prey by birds such as the hawk, and by larger snakes. Their small size also makes the venom of a bee, wasp or spider much more serious than for a larger mammal. For these reasons, an owner should be vigilant when a ferret is outdoors.
 

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