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Viral diseases
Epizootic catarrhal enteritis (ECE)

ECE, a viral disease that first appeared in the northeastern US in 1994, is an inflammation of the mucous membranes in the intestine. The disease manifests itself as severe diarrhea (often of a bright green color), loss of appetite, and severe weight loss. The virus can be passed via fluids and indirectly between humans. Although it was often fatal when first discovered, ECE is less of a threat nowadays with the right supportive care which usually includes hospitalization with intravenous fluids. The virus is especially threatening to older ferrets and requires immediate attention.

Aleutian disease virus (ADV)

Aleutian Disease Virus (ADV) is a parvovirus discovered among mink in the Aleutian Islands in the early 20th century. In ferrets, the virus affects the immune system (causing it to produce non-neutralizing antibodies) and many internal organs, particularly the kidneys. There is no cure or vaccine for the disease, and ferrets may carry the virus for months or years without any external symptoms. As a result, some ferret organizations and shelters recommend that owners test their pets for the virus regularly, separating them from other ferrets if they test positive.

Canine distemper

Canine distemper (CD) is an extremely contagious virus that is almost always fatal. Being strict indoor pets does not necessarily protect ferrets, as owners may bring the virus home on their clothes or their shoes. The only protection against the virus is vaccination, but that is not without controversy as there have been reports, particularly from the USA, of ferrets going into anaphylactic shock after being vaccinated against CD.


Waardenburg-like coloring
Ferrets with a white stripe on their face or a fully white head, primarily blazes, badgers, and pandas, almost certainly carry a congenital defect which shares some similarities to Waardenburg syndrome. This causes, among other things, a cranial deformation in the womb which broadens the skull, causing the white face markings but also partial or total deafness. It is estimated as many as 75% of ferrets with these Waardenburg-like colorings are deaf. Beyond that, the cranial deformation also causes a higher instance of stillborn ferret kits, and occasionally cleft palates. Because of this, many breeders will not breed Waardenburg-patterned ferrets.
 

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